Fighting under a new promoter and broadcaster, undefeated Edwards took his opportunity to win a 20th consecutive contest, with all three judges scoring it 117-111 to the champion.
'Showtime' lived up to his alias, showboating within seconds. Each time Campos missed, Edwards mockingly looking in the direction of the punch thrown.
Campos, 26, may have edged the opening round before it became an Edwards masterclass.
Nonchalantly evading punches, connecting with quick counters and even faster hands, Edwards began to show why many see him as Britain's most technically gifted boxer.
Each time Campos, bidding to become Chile's first world champion, trapped Edwards against the ropes, the Croydon fighter unleashed stinging uppercuts.
"He ain't hitting me now," Edwards told his corner at the end of the fourth.
He has been slightly guilty of complacency in the past when things get comfortable, and a lack of concentration allowed Campos to land a strong body shot making Edwards wince in the sixth.
He began to tire in the second half of the fight and the rounds were becoming closer than they perhaps needed to be, with Campos landing combinations to head and body.
Edwards found a second wind - or maybe switched back on - in the championships rounds, dancing rings around his opponent who continued to come forward.
The champion insisted he needed to not only win, but to win convincingly. He did just that, and next on his agenda is a unification fight with American WBO champion Jesse 'Bam' Rodriguez.
"Bam Rodriguez - where are you?" he said. "I was waiting. Sign the contract. Eddie [Hearn] said sign the contract."
Promoter Hearn guaranteed a unification fight could be next, while Mexico's Julio Cesar Martinez - who holds the WBC belt - is also an option.
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